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Gyre Therapeutics share price today

Gyre Therapeutics, Inc. · GYRE · Healthcare · Biotechnology · price as of the 4 November 2026 close, updated every trading day · results updated weekly · All US stock lists

Gyre Therapeutics share price: $4.44 at the close on 4 November 2026, −38.4% in a year.

$4.44Price −38.4% in a year
$29.1 MRevenue (Jun 2026)
−$11.7 MProfit (Jun 2026)
−47.6%Operating margin
4%ROE FY25
−16.8%ROIC against a 30.1% cost of capital: −46.9 points

Gyre Therapeutics, Inc.'s share price, valuation and earnings point in different directions. The next one or two quarters should make it clearer.

Biggest thing to watch: the price is not yet in a clear uptrend, so timing is the risk more than the business.

The price has been between phases. Over the last four quarters, results have been mixed, and 41% of the last 3 years' profit came in as cash. What will decide it: the next one or two quarters of results.

What is the Gyre Therapeutics share price today?

Gyre Therapeutics, Inc.'s share price was $4.44 at the close on 4 November 2026. That is 36.0% below its average price over the last 200 trading days. In the last 52 weeks it traded between $4 and $8, and at that close it was at the low of that range.

A share price tends to move through four phases: moving sideways (stage 1), rising (stage 2), stalling near a high (stage 3) and falling (stage 4). The phase helps read everything below.

Over the past 13 weeks it has done worse than the S&P 500, and it has been behind for 4 weeks running.

Nov 2026: $4.44, 36.0% below its 200-day average.

  • Price $4.44
  • 50-day avg $6.60
  • 200-day avg $6.94
Nov 2026: $4.44, 36.0% below its 200-day average.
WeekPrice50-day avg200-day avg
11 Jul 2025$7.49––
18 Jul 2025$7.21––
25 Jul 2025$7.64––
1 Aug 2025$6.65––
8 Aug 2025$7.19––
15 Aug 2025$8.14––
22 Aug 2025$8.18––
29 Aug 2025$7.74––
5 Sep 2025$7.69––
12 Sep 2025$7.83––
19 Sep 2025$7.25$7.59–
26 Sep 2025$7.16$7.58–
3 Oct 2025$7.41$7.60–
10 Oct 2025$7.96$7.60–
17 Oct 2025$8.30$7.75–
24 Oct 2025$8.17$7.80–
31 Oct 2025$7.75$7.80–
7 Nov 2025$7.21$7.72–
14 Nov 2025$7.99$7.75–
21 Nov 2025$7.55$7.72–
28 Nov 2025$7.75$7.73–
5 Dec 2025$7.98$7.78–
12 Dec 2025$7.69$7.84–
19 Dec 2025$7.13$7.85–
26 Dec 2025$7.26$7.76–
2 Jan 2026$6.81$7.64–
9 Jan 2026$7.40$7.59–
16 Jan 2026$7.68$7.61–
23 Jan 2026$7.85$7.65–
30 Jan 2026$8.09$7.65–
6 Feb 2026$7.88$7.67–
13 Feb 2026$8.02$7.69–
20 Feb 2026$8.28$7.72–
27 Feb 2026$8.24$7.77–
6 Mar 2026$7.71$7.84–
13 Mar 2026$7.55$7.93–
20 Mar 2026$6.72$7.92–
27 Mar 2026$6.78$7.86–
2 Apr 2026$7.12$7.79–
10 Apr 2026$7.39$7.71–
17 Apr 2026$8.10$7.69–
24 Apr 2026$7.44$7.68$7.67
1 May 2026$7.80$7.63$7.68
8 May 2026$7.47$7.56$7.69
15 May 2026$6.55$7.44$7.68
22 May 2026$6.06$7.26$7.66
29 May 2026$5.91$7.13$7.63
5 Jun 2026$6.29$7.03$7.58
12 Jun 2026$5.93$6.94$7.53
18 Jun 2026$6.25$6.85$7.49
26 Jun 2026$6.29$6.71$7.45
2 Jul 2026$7.34$6.61$7.43
10 Jul 2026$6.52$6.54$7.41
17 Jul 2026$6.05$6.41$7.39
24 Jul 2026$5.94$6.26$7.35
31 Jul 2026$5.75$6.18$7.31
7 Aug 2026$6.67$6.21$7.25
14 Aug 2026$6.68$6.30$7.22
21 Aug 2026$6.91$6.38$7.20
28 Aug 2026$6.59$6.45$7.18
4 Sep 2026$6.86$6.48$7.14
11 Sep 2026$6.73$6.51$7.13
18 Sep 2026$7.55$6.50$7.11
25 Sep 2026$7.35$6.60$7.10
2 Oct 2026$7.11$6.73$7.08
9 Oct 2026$7.04$6.84$7.07
16 Oct 2026$6.08$6.88$7.06
23 Oct 2026$5.85$6.81$7.03
30 Oct 2026$4.55$6.73$6.99
4 Nov 2026$4.44$6.60$6.94
Weekly closing price ($) with its 50-day and 200-day averages. 1-year window.

Week by week since 2025: did it beat the S&P 500 over the past 13 weeks?

Ahead in 20 of 57 weeks

Week by week since 2025: did it beat the S&P 500 over the past 13 weeks?
Week13-week return vs S&P 500
11 Jul 2025no S&P 500 reading
18 Jul 2025no S&P 500 reading
25 Jul 2025no S&P 500 reading
1 Aug 2025no S&P 500 reading
8 Aug 2025no S&P 500 reading
15 Aug 2025no S&P 500 reading
22 Aug 2025no S&P 500 reading
29 Aug 2025no S&P 500 reading
5 Sep 2025no S&P 500 reading
12 Sep 2025no S&P 500 reading
19 Sep 2025no S&P 500 reading
26 Sep 2025no S&P 500 reading
3 Oct 2025no S&P 500 reading
10 Oct 2025+1.6%
17 Oct 2025+9.3%
24 Oct 2025+0.6%
31 Oct 2025+6.8%
7 Nov 2025−5.0%
14 Nov 2025−6.3%
21 Nov 2025−9.8%
28 Nov 2025−5.8%
5 Dec 2025−2.2%
12 Dec 2025−5.5%
19 Dec 2025−4.2%
26 Dec 2025−2.9%
2 Jan 2026−10.2%
9 Jan 2026−13.3%
16 Jan 2026−11.6%
23 Jan 2026−5.7%
30 Jan 2026+2.9%
6 Feb 2026+6.4%
13 Feb 2026−1.1%
20 Feb 2026+5.1%
27 Feb 2026+5.9%
6 Mar 2026−1.4%
13 Mar 2026+1.0%
20 Mar 2026−1.0%
27 Mar 2026+1.5%
2 Apr 2026+8.6%
10 Apr 2026+2.0%
17 Apr 2026+2.8%
24 Apr 2026−8.8%
1 May 2026−7.7%
8 May 2026−12.0%
15 May 2026−26.8%
22 May 2026−35.0%
29 May 2026−38.6%
5 Jun 2026−28.1%
12 Jun 2026−33.5%
18 Jun 2026−22.1%
26 Jun 2026−22.2%
2 Jul 2026−10.5%
10 Jul 2026−22.9%
17 Jul 2026−30.0%
24 Jul 2026−23.7%
31 Jul 2026−29.9%
7 Aug 2026−15.5%
14 Aug 2026−3.0%
21 Aug 2026+11.3%
28 Aug 2026+9.8%
4 Sep 2026+4.6%
11 Sep 2026+10.5%
18 Sep 2026+18.8%
25 Sep 2026+11.0%
2 Oct 2026−6.5%
9 Oct 2026+4.8%
16 Oct 2026−2.2%
23 Oct 2026−4.4%
30 Oct 2026−22.0%
4 Nov 2026−32.6%
Each bar is one week, from 2025 to now (57 weeks with a reading). Green means the stock's return over the previous 13 weeks beat the S&P 500; red means it trailed. The colour is strongest at a gap of 25 percentage points or more. A gap means there is no reading for that week.

Over the last 1 year the share price moved −41% while the S&P 500 moved +23%, so it is behind the index over that whole period. It was last ahead over 13 weeks in the week of 9 October 2026. The chart above shows the 13-week comparison for every week.

This page treats a rise as over when the price closes below its 200-day average on two Fridays in a row.

What dividend does Gyre Therapeutics pay?

Gyre Therapeutics, Inc. pays no dividend. In the last 12 reported quarters it declared no dividend per share, so there is no payout history to chart and no yield to show. Companies like this usually keep their earnings in the business, so the cash-flow sections show where that cash goes.

Which stock lists is Gyre Therapeutics on?

Gyre Therapeutics is not in the Nasdaq 100, the S&P 500 or the Dow Jones 30, and is not on the US tech stocks list.

Is Gyre Therapeutics profitable?

Gyre Therapeutics, Inc. posted a net loss of $11.7 M in the Jun 2026 quarter. Full-year FY25 profit was $5.0 M. That loss is 40.1% of the quarter's revenue. The same quarter a year earlier earned $3.5 M. 4 of the last 8 reported quarters were loss-making.

Net profit is what is left after every cost, interest and tax. Earnings per share, dividends and book value all grow from it.

For the full year, FY25 profit was $5.0 M (−58.4% on the year before).

FY25 profit $5.0 M (−58.4% on the year before)

  • Net profit $5.0 M
FY25 profit $5.0 M (−58.4% on the year before)
QuarterNet profit
FY21−$87.9 M
FY22$2.3 M
FY23−$92.9 M
FY24$12.1 M
FY25$5.0 M

Growth on a year earlier

  • Growth on a year earlier −58.4%
Growth on a year earlier
QuarterGrowth on a year earlier
FY21–
FY22–
FY23−4,137.1%
FY24–
FY25−58.4%
Top: net profit each year, $ M. Below: growth on the year before, %. 5-year window. A grey bar is lower than the year before.

Jun 2026: −$11.7 M

  • Net profit (quarterly) −$11.7 M
Jun 2026: −$11.7 M
QuarterNet profit (quarterly)
Sep 2023$4.0 M
Dec 2023−$101 M
Mar 2024$7.5 M
Jun 2024$3.5 M
Sep 2024$1.1 M
Dec 2024−$0.1 M
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026−$13.1 M
Jun 2026−$11.7 M

Growth on a year earlier

  • Growth on a year earlier −71.7%
Growth on a year earlier
QuarterGrowth on a year earlier
Sep 2023–
Dec 2023–
Mar 2024235.7%
Jun 202490.4%
Sep 2024−71.7%
Dec 2024–
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026–
Jun 2026–
Top: net profit each quarter, $ M. Below: growth on the same quarter a year earlier, %. Last 12 quarters. A grey bar is lower than the quarter before.

How much revenue does Gyre Therapeutics make, and is it growing?

Gyre Therapeutics, Inc. reported $29.1 M of revenue in the Jun 2026 quarter. Over 4 years it has grown 99.6% a year on average. The last full year, FY25, came in at $117 M.

Revenue is everything the company billed its customers in the period.

The quarterly figures for FY25 do not add up to the full-year total on file, so those quarters are left out of the charts and sums.

FY25 revenue was $117 M, +10.2% on the year before.

FY25 revenue $117 M (+10.2% on the year before), 99.6% a year over 4 years

  • Revenue $117 M
FY25 revenue $117 M (+10.2% on the year before), 99.6% a year over 4 years
QuarterRevenue
FY21$7.3 M
FY22$102 M
FY23$113 M
FY24$106 M
FY25$117 M

Growth on a year earlier

  • Growth on a year earlier 10.2%
Growth on a year earlier
QuarterGrowth on a year earlier
FY21–
FY221,294%
FY2310.9%
FY24−6.8%
FY2510.2%
Top: revenue each year, $ M. Below: growth on the year before, %. 5-year window. A grey bar is lower than the year before.

Jun 2026: $29.1 M

  • Revenue (quarterly) $29.1 M
Jun 2026: $29.1 M
QuarterRevenue (quarterly)
Sep 2023$32.0 M
Dec 2023$27.1 M
Mar 2024$27.2 M
Jun 2024$25.2 M
Sep 2024$25.5 M
Dec 2024$27.9 M
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026$24.4 M
Jun 2026$29.1 M

Growth on a year earlier

  • Growth on a year earlier 2.7%
Growth on a year earlier
QuarterGrowth on a year earlier
Sep 20239.8%
Dec 2023−4.7%
Mar 20249%
Jun 2024−14%
Sep 2024−20.5%
Dec 20242.7%
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026–
Jun 2026–
Top: revenue each quarter, $ M. Below: growth on the same quarter a year earlier, %. Last 12 quarters. A grey bar is lower than the quarter before.

How much of every $100 of sales does Gyre Therapeutics keep?

Gyre Therapeutics, Inc.'s operating margin was −47.6% in the Jun 2026 quarter. Across 5 years it has been between −1,197.8% and 16.9%. The latest quarter is within that range.

Operating margin is what is left from every $100 of sales after the costs of running the business, before interest and tax. It shows pricing power and cost control.

Why the margin moved: operating margin changed −60.5 percentage points on the year while gross margin changed −4.5 points. So the drop came mostly from costs below the gross margin, such as staff and overheads, measured against sales.

FY25: 9.9%, within a range of −1,197.8% to 16.9% over 5 years

  • Operating margin 9.9%
FY25: 9.9%, within a range of −1,197.8% to 16.9% over 5 years
QuarterOperating margin
FY21−1,197.8%
FY229%
FY2316.9%
FY2415.3%
FY259.9%

Change on the year before (points)

  • Change on the year before (points) −5.4 pts
Change on the year before (points)
QuarterChange on the year before (points)
FY21–
FY22+1,206.8 pts
FY23+7.9 pts
FY24−1.6 pts
FY25−5.4 pts
Operating margin each year, % (top). Below: change on the year before, in percentage points. 5-year window.

Jun 2026: operating margin −47.6%

  • Operating margin −47.6%
Jun 2026: operating margin −47.6%
QuarterOperating margin
Sep 202339.8%
Dec 2023−19.1%
Mar 202429.7%
Jun 202412.9%
Sep 202416.6%
Dec 20242.4%
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026−51.5%
Jun 2026−47.6%

Change on a year earlier (points)

  • Change on a year earlier (points) +21.5 pts
Change on a year earlier (points)
QuarterChange on a year earlier (points)
Sep 2023+43.9 pts
Dec 2023−14.2 pts
Mar 2024+3.0 pts
Jun 2024−4.1 pts
Sep 2024−23.2 pts
Dec 2024+21.5 pts
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026–
Jun 2026–
Top: quarterly operating margin, %. Below: change on the same quarter a year earlier, in percentage points. Last 12 quarters. Operating profit as a share of revenue, each quarter.

Is Gyre Therapeutics' profit turning into cash?

Over the last 3 years, 41% of Gyre Therapeutics, Inc.'s reported profit came in as cash from its operations, a gap worth watching. In FY25 it brought in $1.0 M of operating cash against $5.0 M of profit. After $1.2 M of spending on assets, free cash was −$180 K: it spent more than its operations brought in.

The profit and loss account shows what was earned. The cash-flow statement shows the cash that actually came in. Comparing operating cash flow with profit is one of the best checks that a profit is real.

Cash-flow figures here are yearly, because quarterly cash statements are not published, so this section changes once a year.

FY25: operating cash $1.0 M against profit $5.0 M; 41% of 3 years' profit came in as cash

  • Operating cash $1.0 M
  • Net profit $5.0 M
  • Free cash −$0.2 M
FY25: operating cash $1.0 M against profit $5.0 M; 41% of 3 years' profit came in as cash
QuarterOperating cashNet profitFree cash
FY21−$83.8 M−$87.9 M−$84.6 M
FY22$10.7 M$2.3 M$5.7 M
FY23$25.9 M−$92.9 M$17.4 M
FY24−$3.6 M$12.1 M−$6.0 M
FY25$1.0 M$5.0 M−$0.2 M
Operating cash flow and net profit each year, $ M. The line is free cash flow: operating cash minus spending on assets. 5-year window, yearly figures.

Jun 2026: operating cash −$16.7 M

  • Operating cash (quarterly) −$16.7 M
Jun 2026: operating cash −$16.7 M
QuarterOperating cash (quarterly)
Sep 2023$7.6 M
Dec 2023$3.4 M
Mar 2024$2.9 M
Jun 2024−$5.5 M
Sep 2024$1.7 M
Dec 2024−$2.8 M
Mar 2025−$0.1 M
Jun 2025−$7.5 M
Sep 2025$4.7 M
Dec 2025−$5.6 M
Mar 2026$3.2 M
Jun 2026−$16.7 M

Operating cash as % of profit

  • Operating cash as % of profit 154%
Operating cash as % of profit
QuarterOperating cash as % of profit
Sep 2023191%
Dec 2023–
Mar 202438%
Jun 2024−156%
Sep 2024154%
Dec 2024–
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026–
Jun 2026–
Top: operating cash each quarter, $ M. Below: operating cash as a % of net profit; 100% means all of the quarter's profit came in as cash. Last 12 quarters.

Why: the cash figure is clear, but the day counts behind it are not in our data, so we show it without guessing the reason.

What to look at next: the main use of cash is spending on assets. The next section checks what that spending is building.

Where does Gyre Therapeutics' cash go?

Gyre Therapeutics, Inc. does not report the customer, stock and supplier day counts a cash cycle needs, so this section looks at its spending on assets instead. It spent $12.0 M on assets over the last 3 years. Averaged over those years that is 3.4% of FY25 revenue a year.

Working capital is the cash tied up between paying suppliers and getting paid. Debtor days: how long customers take to pay. Inventory days: how long stock sits. The cash cycle: the whole loop, in days of sales.

Nothing is estimated in place of the missing day counts, so no cash-cycle chart is drawn.

Spending on assets: $12.0 M over the last 3 years.

FY25: capex $1.2 M, down from the year before

  • Capex $1.2 M
FY25: capex $1.2 M, down from the year before
QuarterCapex
FY21$0.8 M
FY22$5.0 M
FY23$8.5 M
FY24$2.3 M
FY25$1.2 M
Capital spending each year, $ M.

Jun 2026: capex $0.3 M in the quarter

  • Capex (quarterly) $0.3 M
Jun 2026: capex $0.3 M in the quarter
QuarterCapex (quarterly)
Sep 2023$2.0 M
Dec 2023$2.3 M
Mar 2024$0.2 M
Jun 2024$1.5 M
Sep 2024$0.7 M
Dec 2024$0.1 M
Mar 2025$0.1 M
Jun 2025$0.3 M
Sep 2025$0.7 M
Dec 2025$0.1 M
Mar 2026$0.2 M
Jun 2026$0.3 M

Free cash

  • Free cash −$17.0 M
Free cash
QuarterFree cash
Sep 2023$5.6 M
Dec 2023$1.0 M
Mar 2024$2.7 M
Jun 2024−$6.9 M
Sep 2024$1.0 M
Dec 2024−$2.7 M
Mar 2025−$0.3 M
Jun 2025−$7.8 M
Sep 2025$4.0 M
Dec 2025−$5.8 M
Mar 2026$3.0 M
Jun 2026−$17.0 M
Top: capital spending each quarter, $ M. Below: free cash flow, $ M. Last 12 quarters.

In short: the cash is going into new capacity, not getting stuck in the daily cycle. The question is whether the new capacity earns.

What is Gyre Therapeutics' P/E ratio, and how does it compare with its own history?

Gyre Therapeutics, Inc. has no P/E right now, because its earnings are negative. The revenue and margin sections are where a turn would show first. Measured against sales instead, the market values Gyre Therapeutics, Inc. at 4.0× its FY25 revenue of $117 M. The P/E comes back here once profit turns positive.

P/E is the share price divided by a year's profit per share: how many dollars the market pays for each dollar of yearly profit.

—P/E · earnings negative
n/mPEG · cannot be worked out, because 3-year earnings growth is not available

Why the multiple is where it is: over the past year earnings per share moved −53.2% while the price moved −38.4%. The price did better than earnings, which pushed the multiple up within its own range.

Is the Gyre Therapeutics business getting better or worse?

Gyre Therapeutics, Inc.'s business trend cannot be read yet. There are fewer than eight usable quarters of growth figures, so there is not enough history to read the trend. This is based on 6 quarters of 1 measure, with some gaps.

Every business is somewhere on a path of getting better or worse, and this section names where. The last 12 quarters of growth in revenue, profit and earnings per share, plus the return the business earns on its capital, are read as lines. Getting worse: the lines are falling. Turning around: a low point has just formed and the last few quarters are rising from it. Getting better: the rise from the low has lasted. Growing steadily: steady growth with healthy returns. Slowing from a peak: still high, but slowing. When the lines disagree the result is mixed; too little history means no reading. CAGR (compound annual growth rate) is the steady yearly rate that would turn the starting value into the latest one. It is the fairest way to compare growth over different periods. If the 1-year figure is much bigger than the 10-year one, recent growth is running faster than the long-run trend. A dash means there is no figure for that period, or the starting year was a loss, where a growth rate means nothing.

Growth year by year: revenue +10.2% in FY25, profit −58.4%

  • Revenue growth 10.2%
Growth year by year: revenue +10.2% in FY25, profit −58.4%
QuarterRevenue growth
FY21–
FY221,294%
FY2310.9%
FY24−6.8%
FY2510.2%

Profit growth, EPS growth

  • Profit growth −58.4%
  • EPS growth −53.2%
Profit growth, EPS growth
QuarterProfit growthEPS growth
FY21––
FY22–−87.5%
FY23−300%−300%
FY24––
FY25−58.4%−53.2%
Growth on the year before, each year, %. Top: revenue. Below: net profit and earnings per share, on their own scale because profit growth swings much more. Zero line drawn. Turnaround-year jumps are drawn at the edge (▲).

Three growth lines over twelve quarters

  • Revenue −6.8%
Three growth lines over twelve quarters
QuarterRevenue
Sep 202344.2%
Dec 20237.4%
Mar 20249.2%
Jun 2024−0.3%
Sep 2024−8.5%
Dec 2024−6.8%
Mar 2025–
Jun 2025–
Sep 2025–
Dec 2025–
Mar 2026–
Jun 2026–

Profit, EPS

  • Profit −71.7%
  • EPS −300%
Profit, EPS
QuarterProfitEPS
Sep 2023––
Dec 2023––
Mar 2024235.7%–
Jun 202490.4%–
Sep 2024−71.7%−300%
Dec 2024––
Mar 2025––
Jun 2025––
Sep 2025––
Dec 2025––
Mar 2026––
Jun 2026––
Growth on a year earlier, % at each quarter end. Top: revenue. Below: profit and earnings per share, on their own scale because they swing much more. Each is measured over the last 12 months. Where the 12-month history is short, the line uses single-quarter growth instead, which is noisier; extreme jumps from a tiny base are evened out before reading. Extreme jumps from a tiny base are drawn at the edge (▲). A gap means there is no reading for that quarter.

ROE: the return line, yearly figures

  • ROE 3.5%
ROE: the return line, yearly figures
QuarterROE
FY223.2%
FY23−118.4%
FY2412.3%
FY253.5%
Yearly figures: the quarterly balance-sheet figures this line needs are not available for this stock, so it changes once a year and counts for less in the reading.
Stuck lowROE · latest 3.5%, range −118.4% to 12.3%

Why it matters: with too little history, we say so rather than guess a direction.

The latest quarter’s profit includes a one-off item bigger than the normal business, so the profit line is shown but does not count in this reading.

One or more growth lines have an extreme jump caused by comparing with a near-zero or loss-making quarter. Those jumps are capped before reading and drawn at the edge of the chart, so one odd quarter does not decide the result.

The return figures here are yearly, not quarterly. They show level and direction only; they can support the growth lines but never decide the reading alone.

There are fewer than eight usable quarters, so this page does not guess a direction from so little history.

Compound annual growth rate (%)

Compound annual growth rate over each period, %. Revenue, profit and EPS come from yearly figures; the stock price row is price growth over the same periods. A dash means no figure for that period, or the starting year was a loss.

Compound annual growth rate (%)
Measure1yr3yr5yr10yr
Revenue+10.2%+4.5%——
Profit−58.4%+29.7%——
EPS−53.2%−9.2%——
Stock price−38.4%———

How much does Gyre Therapeutics earn on its capital?

Gyre Therapeutics, Inc. earned a ROE of 4% in FY25. That is up from a low of −214% in FY21. Its return on capital used (ROIC) is 46.9 percentage points below its cost of capital, so growth here does not yet pay for the capital it uses.

Return on equity (ROE) is the profit the business earns on its shareholders’ money. We do not have the full capital split, so ROE is the longest history we can draw here.

It comes from a 4.3% net margin and 0.70× asset turnover (sales divided by assets).

Why the return is what it is (FY25): a 4.3% net margin × 0.70× asset turnover × 1.17× leverage (assets divided by equity) ≈ 3.5% on equity. The margin does its share; borrowing plays a small part, so this return is earned, not borrowed.

The key test, return on capital used minus the cost of capital: −16.8% − 30.1% = −46.9 percentage points. The 30.1% is an estimate of this company's own cost of capital. Read the sign and size of the gap, not the decimals. Negative: growth at these returns loses value until returns improve.

The −16.8% ROIC above is the latest reading, as reported. The yearly chart below shows FY25 at 9.6%, and the quarterly chart works out each 12-month window from the quarterly figures, so the readings differ by date, not by method.

FY25: ROE 4%, the climb back from FY21's −214%

  • ROE 3.5%
  • ROIC (annual) 9.6%
  • Cost of capital 30.1%
FY25: ROE 4%, the climb back from FY21's −214%
QuarterROEROIC (annual)Cost of capital
FY21−214%–30.1%
FY223.2%8.9%30.1%
FY23−118.4%41.3%30.1%
FY2412.3%21.1%30.1%
FY253.5%9.6%30.1%
Return on equity each year, % (line); ROIC each year, % (line). 5-year window, low years included. The flat line is the 30.1% cost of capital used on this page.

Jun 2026: ROIC −9.9% (last 12 months) against a 30.1% cost of capital

  • ROIC (12 months) −9.9%
  • ROE (12 months) −47%
  • Cost of capital 30.1%
Jun 2026: ROIC −9.9% (last 12 months) against a 30.1% cost of capital
QuarterROIC (12 months)ROE (12 months)Cost of capital
Sep 2023–−7.2%30.1%
Dec 202323%58.3%30.1%
Mar 202417.3%−386.8%30.1%
Jun 202421.1%−362.7%30.1%
Sep 202419.9%−360.6%30.1%
Dec 202412.8%−379.5%30.1%
Mar 202522.1%81.6%30.1%
Jun 202511.8%53.6%30.1%
Sep 20254.9%26%30.1%
Dec 20257.7%31.9%30.1%
Mar 20267.1%25.7%30.1%
Jun 2026−9.9%−47%30.1%
ROIC and ROE over the last 12 months, each quarter, %; the flat line is the cost of capital. Last 12 quarters, lined up with the yearly figure.

Does Gyre Therapeutics have too much debt?

Gyre Therapeutics, Inc. has total debt of $3.4 M against shareholder equity of $165 M as of Jun 2026, so its debt is 0.02× its equity, which is very little. Year by year, that ratio went from 0.06 in FY21 to 0.01 in FY25. So the returns on this page come from the business, not from borrowed money.

Debt-to-equity shows how much of the business is paid for with borrowed money. Lower is safer, and the direction matters as much as the level.

FY25: debt $0.9 M, 0.01× equity

  • Total debt $0.9 M
FY25: debt $0.9 M, 0.01× equity
QuarterTotal debt
FY21$2.4 M
FY22$0.6 M
FY23$0.4 M
FY24$1.6 M
FY25$0.9 M

Debt-to-equity

  • Debt-to-equity 0.01×
Debt-to-equity
QuarterDebt-to-equity
FY210.06×
FY220.01×
FY230.01×
FY240.02×
FY250.01×
Top: total debt each year, $ M. Below: debt-to-equity, ×. 5-year window.

Jun 2026: debt $3.4 M, debt-to-equity 0.02

  • Total debt (quarterly) $3.4 M
Jun 2026: debt $3.4 M, debt-to-equity 0.02
QuarterTotal debt (quarterly)
Sep 2023$0.5 M
Dec 2023$0.4 M
Mar 2024$0.3 M
Jun 2024$2.0 M
Sep 2024$1.8 M
Dec 2024$1.6 M
Mar 2025$1.6 M
Jun 2025$1.4 M
Sep 2025$1.2 M
Dec 2025$0.9 M
Mar 2026$0.8 M
Jun 2026$3.4 M

Debt-to-equity

  • Debt-to-equity 0.02×
Debt-to-equity
QuarterDebt-to-equity
Sep 20230.00×
Dec 20230.01×
Mar 20240.00×
Jun 20240.02×
Sep 20240.02×
Dec 20240.02×
Mar 20250.02×
Jun 20250.01×
Sep 20250.01×
Dec 20250.01×
Mar 20260.01×
Jun 20260.02×
Top: total debt each quarter, $ M. Below: debt-to-equity, ×. Last 12 quarters.

What is the Gyre Therapeutics shareholding pattern?

5.4% of Gyre Therapeutics, Inc.'s tradable shares are in short positions, which are bets that the price will fall, so some traders are betting against it. At normal trading volumes, closing those positions would take about 9.8 days. US companies do not publish a quarter-by-quarter list of owners, so this page uses short interest instead.

There is no quarter-by-quarter list of owners here, so we look at short interest: the share of tradable shares held in short positions, which gain if the price falls.

It is a single reading at one point in time; we do not have its history.

5.4%Short interest · of the tradable float
9.8Days to cover · at typical volumes

Why it is at this level: the figure does not say who has the short positions or why, so we show the level without guessing the story.

How far is Gyre Therapeutics from balance-sheet trouble?

For Gyre Therapeutics, Inc., the Z-score is 11.85. A Z-score above about 3 is safe and below about 1.8 signals danger, so this is well clear of danger. It estimates how far the balance sheet is from trouble; it is not a forecast of failure.

The Z-score estimates how far a company is from balance-sheet trouble. Above about 3 is safe; below about 1.8 is the danger zone. It was built for manufacturers, so it is not used for banks and lenders.

Why it matters: a Z-score of 11.85 is well clear of the danger zone, so the balance sheet is not the risk here.

How does Gyre Therapeutics rank in its industry?

There is no score against its industry: Gyre Therapeutics, Inc. is not among the largest members shown in this industry comparison for Biotechnology.

The score ranks a company within its industry: each measure is scored against the other members. Without that group there is no score, so none is shown.

Which companies is Gyre Therapeutics compared with?

No sector comparison is shown here, not among the largest members shown in this industry comparison.

Which companies are close to Gyre Therapeutics in size?

Gyre Therapeutics is the 146th largest of 211 Biotechnology companies on Sector Alpha by market value (scores of 4 November 2026). Just above it: REGENXBIO Inc., YD Bio and Arvinas, Inc. Just below it: MiMedx Group, Inc., Phathom Pharmaceuticals, Inc. and Oculis Holding AG.

Biotechnology companies close in size

  1. REGENXBIO Inc. $509 million
  2. YD Bio Limited $492 million
  3. Arvinas, Inc. $486 million
  4. Gyre Therapeutics, Inc. $471 million
  5. MiMedx Group, Inc. $467 million
  6. Phathom Pharmaceuticals, Inc. $451 million
  7. Oculis Holding AG $449 million

All 211 Biotechnology companies, largest first

Companies close in size in other industries

  1. Cerus Corporation $472 million · Medical Devices
  2. Oculis Holding AG $471 million · Biotechnology
  3. Gyre Therapeutics, Inc. $471 million
  4. Ovid Therapeutics Inc. $469 million · Biotechnology
  5. Senseonics Holdings, Inc. $468 million · Medical Devices

What else do people ask about Gyre Therapeutics?

What were Gyre Therapeutics's latest quarterly results?

Gyre Therapeutics, Inc. reported revenue of $29.1 M and a net loss of $11.7 M for the Jun 2026 quarter. Earnings per share were −$0.12. The operating margin was −47.6% (as of 4 November 2026).

What is Gyre Therapeutics's market cap?

Gyre Therapeutics, Inc.'s market capitalisation is $471 M at a stock price of $4.44. Market cap is the share price times the number of shares, so it changes whenever the price moves (as of 4 November 2026).

How is Gyre Therapeutics performing?

Gyre Therapeutics, Inc.'s latest readings are below. Over the past 13 weeks it has done worse than the S&P 500, for 4 weeks running. This describes what the data did, not a rating (as of 4 November 2026).

Will Gyre Therapeutics's stock price go up?

This page does not forecast Gyre Therapeutics, Inc.'s stock price. What it shows instead: the stock price is $4.44. Nobody can reliably say which way a price will move, and this site does not try (as of 4 November 2026).

Where is Gyre Therapeutics in its business cycle?

Gyre Therapeutics, Inc.'s FY25 operating margin was 9.9%, against a 5-year range of −1,197.8% to 16.9%: the middle of its own range, neither a peak nor a low. The latest quarter was −47.6%.

Comparing margins with a company's own long history is a good way to see where it is in its cycle (as of 4 November 2026).

What could break the Gyre Therapeutics story?

Biggest thing to watch: the price is not yet in a clear uptrend, so timing is the risk more than the business.

On price, this page treats a rise as over when the share price closes below its 200-day average on two Fridays in a row (as of 4 November 2026).

Is Gyre Therapeutics a stock worth studying right now?

What the numbers show: Gyre Therapeutics, Inc.'s share price, valuation and earnings point in different directions. The next one or two quarters should make it clearer. The main open question: the next one or two quarters of results.

Every number on this page is worked out by code from the published figures, with no forecasts and no price opinions (as of 4 November 2026).

Where do these numbers come from?

Sector Alpha, written by code from the published numbers. Data as of 4 November 2026.

Every chart on this page is drawn by code from the published figures, with no forecasts and no price opinions.

See the plain-text version of this page.

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