# Orchestra BioMed Holdings share price today (Orchestra BioMed Holdings, Inc., OBIO)

> Orchestra BioMed Holdings, Inc.'s share price, valuation and earnings point in different directions. The next one or two quarters should make it clearer. OBIO · Healthcare · Biotechnology · data as of 4 November 2026. Page: https://www.sectoralpha.in/us/stocks/obio

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## Key numbers

- Price: $6.00 (+57.5% in a year)
- Revenue (Jun 2026): $88.0 K
- Profit (Jun 2026), incl. one-off: −$24.1 M (one-off item, see below)
- Operating margin: −25,404.5% (−23,092.7 points on a year ago)
- ROE: −84%, FY25
- ROIC: −62.0%, against a 7.1% cost of capital: −69.1 points

Biggest thing to watch: the price is not yet in a clear uptrend, so timing is the risk more than the business. ## What is the Orchestra BioMed Holdings share price today? Orchestra BioMed Holdings, Inc.'s share price was $6.00 at the close on 4 November 2026. That is 31.6% above its average price over the last 200 trading days. In the last 52 weeks it traded between $3 and $6, and at that close it sat 95% of the way up from that low. Over the past 13 weeks it has done better than the S&P 500, and it has stayed ahead for 14 weeks in a row. Over the last 1 year the share price moved +105% while the S&P 500 moved +18%, so it is ahead of the index over that whole period. The chart above shows the 13-week comparison for every week. This page treats a rise as over when the price closes below its 200-day average on two Fridays in a row. ## What dividend does Orchestra BioMed Holdings pay? Orchestra BioMed Holdings, Inc. pays no dividend. In the last 12 reported quarters it declared no dividend per share, so there is no payout history to chart and no yield to show. Companies like this usually keep their earnings in the business, so the cash-flow sections show where that cash goes. ## Which stock lists is Orchestra BioMed Holdings on? Orchestra BioMed Holdings is not in the Nasdaq 100, the S&P 500 or the Dow Jones 30, and is not on the US tech stocks list. ## Is Orchestra BioMed Holdings profitable? Orchestra BioMed Holdings, Inc. posted a net loss of $24.1 M in the Jun 2026 quarter. That quarter includes a one-off gain bigger than its revenue, so the comparison with last year does not reflect normal business. The full FY25 year was a loss of $53.0 M. That loss is 27,362.5% of the quarter's revenue. The same quarter a year earlier lost $19.4 M. 11 of the last 12 reported quarters were loss-making. Read this profit with care: at −$24.1 M it is bigger than the quarter's whole revenue of $88.0 K. No business earns more than it takes in from sales, so this is a one-off item (for example a debt settlement, a tax write-back or an asset sale), not money the business earned. The underlying business is running at a −25,404.5% operating margin. The jump on last year, and any P/E built on this profit, come from the one-off, not from a real turn in earnings. ## How much revenue does Orchestra BioMed Holdings make, and is it growing? Orchestra BioMed Holdings, Inc. reported $88.0 K of revenue in the Jun 2026 quarter, −89.5% on the same quarter a year earlier. The last full year, FY25, came in at $33.5 M. The last four reported quarters add to $32.0 M. A growth rate over several years is not shown, because there are too few years of figures to work one out properly. FY25 revenue was $33.5 M, +1,169.2% on the year before. Is growth speeding up? Revenue over the last 12 months grew +986.1%, against +292.2% a year over the last 8 quarters (accelerating). ## How much of every $100 of sales does Orchestra BioMed Holdings keep? Orchestra BioMed Holdings, Inc.'s operating margin was −25,404.5% in the Jun 2026 quarter, 23,092.7 percentage points lower than the same quarter a year ago. Across 5 years it has been between −2,437.5% and 2,787.6%. The latest quarter is below every full year in that period. Why the margin moved: operating margin changed −23,092.7 percentage points on the year while gross margin changed −22.9 points. So the drop came mostly from costs below the gross margin, such as staff and overheads, measured against sales. ## Is Orchestra BioMed Holdings' profit turning into cash? Orchestra BioMed Holdings, Inc.'s cash-flow history is too short to judge how much of its profit turns into cash. In FY25 its operations used $49.0 M of cash, against −$53.0 M of profit. After $489 K of spending on assets, free cash was −$49.5 M: it spent more than its operations brought in. Cash-flow figures here are yearly, because quarterly cash statements are not published, so this section changes once a year. What to look at next: the main use of cash is spending on assets. The next section checks what that spending is building. ## Where does Orchestra BioMed Holdings' cash go? Orchestra BioMed Holdings, Inc. does not report the customer, stock and supplier day counts a cash cycle needs, so this section looks at its spending on assets instead. It spent $856 K on assets over the last 3 years. Averaged over those years that is 0.9% of FY25 revenue a year. Nothing is estimated in place of the missing day counts, so no cash-cycle chart is drawn. Spending on assets: $856 K over the last 3 years. In short: most of the cash goes on covering the loss, not on new assets; spending on assets is small next to it. ## What is Orchestra BioMed Holdings' P/E ratio, and how does it compare with its own history? Orchestra BioMed Holdings, Inc. has no P/E right now, because its earnings are negative. The revenue and margin sections are where a turn would show first. Measured against sales instead, the market values Orchestra BioMed Holdings, Inc. at 10.8× its FY25 revenue of $33.5 M. The P/E comes back here once profit turns positive. ## Is the Orchestra BioMed Holdings business getting better or worse? Orchestra BioMed Holdings, Inc.'s business trend cannot be read yet. There are fewer than eight usable quarters of growth figures, so there is not enough history to read the trend. This is based on 11 quarters of 2 measures, with some gaps. Why it matters: with too little history, we say so rather than guess a direction. The latest quarter’s profit includes a one-off item bigger than the normal business, so the profit line is shown but does not count in this reading. The return figures here are yearly, not quarterly. They show level and direction only; they can support the growth lines but never decide the reading alone. There are fewer than eight usable quarters, so this page does not guess a direction from so little history. ## How much does Orchestra BioMed Holdings earn on its capital? Orchestra BioMed Holdings, Inc. earned a ROE of −84% in FY25. That is up from a low of −185% in FY24. Its return on capital used (ROIC) is 69.1 percentage points below its cost of capital, so growth here does not yet pay for the capital it uses. It comes from a −158.2% net margin and 0.29× asset turnover (sales divided by assets). Why the return is what it is (FY25): a −158.2% net margin × 0.29× asset turnover × 1.81× leverage (assets divided by equity) ≈ −83.0% on equity. The margin does its share; borrowing is a big part of it. The key test, return on capital used minus the cost of capital: −62.0% − 7.1% = −69.1 percentage points. The 7.1% is an estimate of this company's own cost of capital. Read the sign and size of the gap, not the decimals. Negative: growth at these returns loses value until returns improve. ## Does Orchestra BioMed Holdings have too much debt? Orchestra BioMed Holdings, Inc. has total debt of $70.8 M against shareholder equity of $29.4 M as of Jun 2026, so its debt is 2.41× its equity. Year by year, that ratio went from −0.29 in FY21 to 0.51 in FY25. Keep that borrowing in mind when reading the returns on this page. ## What is the Orchestra BioMed Holdings shareholding pattern? 7.7% of Orchestra BioMed Holdings, Inc.'s tradable shares are in short positions, which are bets that the price will fall, so some traders are betting against it. At normal trading volumes, closing those positions would take about 8.1 days. US companies do not publish a quarter-by-quarter list of owners, so this page uses short interest instead. It is a single reading at one point in time; we do not have its history. Why it is at this level: the figure does not say who holds the short positions or why, so we show the level without guessing the story. ## How far is Orchestra BioMed Holdings from balance-sheet trouble? For Orchestra BioMed Holdings, Inc., the Z-score is −3.83. A Z-score above about 3 is safe and below about 1.8 signals danger, so this is in the danger zone. It estimates how far the balance sheet is from trouble; it is not a forecast of failure. Why it matters: a Z-score of −3.83 is inside the danger zone, so the balance sheet is a real risk. ## How does Orchestra BioMed Holdings rank in its industry? There is no score against its industry: Orchestra BioMed Holdings, Inc. is not among the largest members shown in this industry comparison for Biotechnology. The score ranks a company within its industry: each measure is scored against the other members. Without that group there is no score, so none is shown. ## Which companies is Orchestra BioMed Holdings compared with? No sector comparison is shown here, not among the largest members shown in this industry comparison. ## Which companies are close to Orchestra BioMed Holdings in size? Orchestra BioMed Holdings is the 162nd largest of 211 Biotechnology companies on Sector Alpha by market value (scores of 5 November 2026). Just above it: Lyell Immunopharma, Inc., Autolus Therapeutics plc and Fennec Pharmaceuticals Inc. Just below it: Opus Genetics, Inc., ProKidney Corp. and Alector, Inc. ### Biotechnology companies close in size

1. [Lyell Immunopharma, Inc.](https://www.sectoralpha.in/us/stocks/lyel) $378 million
2. [Autolus Therapeutics plc](https://www.sectoralpha.in/us/stocks/autl) $367 million
3. [Fennec Pharmaceuticals Inc.](https://www.sectoralpha.in/us/stocks/fenc) $363 million
4. Orchestra BioMed Holdings, Inc. $361 million
5. [Opus Genetics, Inc.](https://www.sectoralpha.in/us/stocks/ird) $355 million
6. [ProKidney Corp.](https://www.sectoralpha.in/us/stocks/prok) $339 million
7. [Alector, Inc.](https://www.sectoralpha.in/us/stocks/alec) $338 million

[All 211 Biotechnology companies, largest first](https://www.sectoralpha.in/us/sectors/biotechnology#all-companies)

### Companies close in size in other industries

1. [J.Jill, Inc.](https://www.sectoralpha.in/us/stocks/jill) $335 million · Apparel Retail
2. [NLI Holdings, Inc.](https://www.sectoralpha.in/us/stocks/nl) $334 million · Security & Protection Services
3. Orchestra BioMed Holdings, Inc. $334 million
4. [Auna S.A.](https://www.sectoralpha.in/us/stocks/auna) $334 million · Medical Care Facilities
5. [Forafric Global PLC](https://www.sectoralpha.in/us/stocks/afri) $334 million · Farm Products

## What else do people ask about Orchestra BioMed Holdings? ### What were Orchestra BioMed Holdings's latest quarterly results? Orchestra BioMed Holdings, Inc. reported revenue of $88.0 K and a net loss of $24.1 M for the Jun 2026 quarter. Earnings per share were −$0.38. The operating margin was −25,404.5%, 23,092.7 percentage points lower than a year earlier (as of 4 November 2026). ### What is Orchestra BioMed Holdings's market cap? Orchestra BioMed Holdings, Inc.'s market capitalisation is $361 M at a stock price of $6.00. Market cap is the share price times the number of shares, so it changes whenever the price moves (as of 4 November 2026). ### How is Orchestra BioMed Holdings performing? Orchestra BioMed Holdings, Inc.'s latest readings are below. Over the past 13 weeks it has done better than the S&P 500, for 14 weeks running. This describes what the data did, not a rating (as of 4 November 2026). ### Will Orchestra BioMed Holdings's stock price go up? This page does not forecast Orchestra BioMed Holdings, Inc.'s stock price. What it shows instead: the stock price is $6.00. Nobody can reliably say which way a price will move, and this site does not try (as of 4 November 2026). ### Where is Orchestra BioMed Holdings in its business cycle? Orchestra BioMed Holdings, Inc.'s FY25 operating margin was −154.7%, against a 5-year range of −2,437.5% to 2,787.6%: the middle of its own range, neither a peak nor a low. The latest quarter was −25,404.5%. Comparing margins with a company's own long history is a good way to see where it is in its cycle (as of 4 November 2026). ### What could break the Orchestra BioMed Holdings story? Biggest thing to watch: the price is not yet in a clear uptrend, so timing is the risk more than the business. On price, this page treats a rise as over when the share price closes below its 200-day average on two Fridays in a row (as of 4 November 2026). ### Is Orchestra BioMed Holdings a stock worth studying right now? What the numbers show: Orchestra BioMed Holdings, Inc.'s share price, valuation and earnings point in different directions. The next one or two quarters should make it clearer. The main open question: the next one or two quarters of results. Every number on this page is worked out by code from the published figures, with no forecasts and no price opinions (as of 4 November 2026). This is research, not advice. We’re not SEBI-registered.